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* Dryness of the skin, lips and nose * Increased sensitivity to the sun * Chapped lips * Skin irritation or dryness * Headaches * Fatigue * Nausea It's important to note that these side effects are usually mild and go away on their own after a few weeks. However, if you experience any severe or persistent side effects while taking Accutane, it's important to talk to your doctor right away. It's also worth noting that Accutane can have serious side effects, including: * Increased risk of depression and suicidal thoughts * Increased risk of birth defects if taken during pregnancy * Elevated liver enzymes Because of these potential risks, it's important to follow your doctor's instructions carefully while taking Accutane. They may recommend regular checkups and blood tests to monitor your health and make sure that the medication is safe for you to continue taking. If you experience any unusual side effects or have concerns about your treatment, be sure to talk to your doctor right away.